Saroglitazar
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CAS No. | 495399-09-2 | Cat. No. | BCP25470 |
Name | Saroglitazar | ||
Synonyms | Lipaglyn; | ||
SMILES | |||
Chemical Name | |||
Formula | C25H29NO4S | M. Wt | 439.57 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Saroglitazar is a drug for the treatment of type 2 diabetes mellitus and dyslipidemia. It is approved for use in India by the Drug Controller General of India. Saroglitazar has demonstrated reduction of triglycerides (TG), LDL cholesterol, VLDL cholesterol, non-HDL cholesterol and an increase in HDL cholesterol a characteristic hallmark of atherogenic diabetic dyslipidemia (ADD). Saroglitazar is novel first in class drug which acts as a dual PPAR agonist at the subtypes α (alpha) and γ (gamma) of the peroxisome proliferator-activated receptor (PPAR). Agonist action at PPARα lowers high blood triglycerides, and agonist action on PPARγ improves insulin resistance and consequently lowers blood sugar. |
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