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CAS No. | 508-02-1 | Cat. No. | BCP10498 |
Name | Oleanolicacid | ||
Synonyms | Oleanic acid; Caryophyllin;Astrantiagenin C; | ||
SMILES | CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C | ||
Chemical Name | |||
Formula | C30H48O3 | M. Wt | 456.71 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Oleanolic Acid is a GPBA receptor (TGR5) partial agonist (EC50 = 2.25 μM; 72% efficacy). It displays no activity at FXR. Also inhibits protein phosphate 1B (PTP1B) and glycogen phosphorylase. Suppresses cell proliferation and increases apoptosis in T24 bladder cancer cells. Antidiabetic, antihyperglycaemic, antitumor and hepatoprotective. |
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