Procaine hydrochloride
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CAS No. | 51-05-8 | Cat. No. | BCP28535 |
Name | Procaine hydrochloride | ||
Synonyms | Procaine Hcl; Novocaine hydrochloride; | ||
SMILES | |||
Chemical Name | |||
Formula | C13H21ClN2O2 | M. Wt | 272.77 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Procaine Hydrochloride is a noted sodium channel blocker with a variety of inhibitory effects. In skeletal muscle, Procaine hydrochloride has been reported to inhibit calcium-induced calcium release (CICR). Procaine is also noted to act as a DNA methylation inhibitor and to cause demethylation and reactivation of methylation-silenced genes such as RARβ and GSTP1. WIF-1 is noted to be reactivated in a cancer cell line and to downregulate the Wnt canonical pathway. In studies utilizing a neuroblastoma cell line, Procaine is reported to induce neuronal apoptosis in a manner correlated with lipid solubility of the compound. |
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