Angiotensin 1-7
Data Sheet
For research use only. Not for human use.
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| CAS No. | 51833-78-4 | Cat. No. | BCP19018 |
| Name | Angiotensin 1-7 | ||
| Synonyms | TXA127; TXA 127; TXA127; Angiotensin i (1-7); therapeutic angiotensin(17); | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C41H62N12O11 | M. Wt | 899.02 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Angiotensin i (1-7) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) with vasodilator and antiproliferative activities. Therapeutic angiotensin 1-7 may inhibit cyclooxygenase 2 (COX-2) and the production of proinflammatory prostaglandins and may activate the angiotensin-(1-7) receptor Mas, resulting in diminished tumor cell proliferation. Activation of the angiotensin-(1-7) receptor Mas, a G-protein coupled, seven transmembrane protein, may down-regulate the phophorylation and activation of Erk1 and Erk2 in the Erk1/Erk2 Mapk signaling pathway. | ||
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