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T-5224 Chemical Structure

T-5224

Data Sheet For research use only. Not for human use.
Cat. No. :BCP14701CAS No. :530141-72-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 530141-72-1 Cat. No. BCP14701
Name T-5224
Synonyms T 5224;T5224;
SMILES OC1=NOC2=CC(COC3=C(CCC(O)=O)C=C(C(C4=C(O)C=C(OC5CCCC5)C=C4)=O)C=C3)=CC=C21
Chemical Name
Formula C29H27NO8 M. Wt 517.53
Purity 98% Storage Store at 4-8°C
Description T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T-5224 has been investigated in phase II human clinical trials. T-5224 may be a promising new treatment for septic kidney injury. Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of cellular processes including proliferation, apoptosis, differentiation, survival, cell migration, and transformation.
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