UF 010
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CAS No. | 537672-41-6 | Cat. No. | BCP16853 |
Name | UF 010 | ||
Synonyms | UF-010;UF010; | ||
SMILES | |||
Chemical Name | |||
Formula | C11H15BrN2O | M. Wt | 271.15 |
Purity | 98% | Storage | Store at 4-8°C |
Description | UF010 is a competitive inhibitor with a fast-on/slow-off HDAC-binding mechanism. UF010 induces accumulation of acetylated histones in HCT116 cells in vitro, arrests cells at G1/S transition. It inhibits proliferation of a range of cancer cell lines. UF010 activates tumor suppression mechanisms while inhibiting oncogenic pathways. |
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