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Chloramphenicol Chemical Structure

Chloramphenicol

Data Sheet For research use only. Not for human use.
Cat. No. :BCP12150CAS No. :56-75-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 56-75-7 Cat. No. BCP12150
Name Chloramphenicol
Synonyms Chloromycetin;Chloroptic;CAP;CAF;CAM;
SMILES
Chemical Name
Formula C11H12Cl2N2O5 M. Wt 323.13
Purity 98% Storage Store at 4-8°C
Description Chloramphenicol is a bacteriostatic drug that stops bacterial growth by inhibiting protein synthesis. Chloramphenicol prevents protein chain elongation by inhibiting the peptidyl transferase activity of the bacterial ribosome. It specifically binds to A2451 and A2452 residues in the 23S rRNA of the 50S ribosomal subunit, preventing peptide bond formation. While chloramphenicol and the macrolide class of antibiotics both interact with ribosomes, chloramphenicol is not a macrolide. It directly interferes with substrate binding, whereas macrolides sterically block the progression of the growing peptide.
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