Dextromethadone New
Data Sheet
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| CAS No. | 5653-80-5 | Cat. No. | BCP49227 |
| Name | Dextromethadone | ||
| Synonyms | Esmethadone;S-Methadone; | ||
| SMILES | CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2 | ||
| Chemical Name | |||
| Formula | C21H27NO | M. Wt | 309.4 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Dextromethadone is a 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder. It has a role as a NMDA receptor antagonist and an opioid analgesic. It is an enantiomer of a levomethadone. | ||
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