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CAS No. | 565460-15-3 | Cat. No. | BCP19101 |
Name | URB602 | ||
Synonyms | URB-602;URB 602; | ||
SMILES | O=C(OC1CCCCC1)NC2=CC(C3=CC=CC=C3)=CC=C2 | ||
Chemical Name | |||
Formula | C19H21NO2 | M. Wt | 295.38 |
Purity | 98% | Storage | Store at 4-8°C |
Description | URB602 is a selective, noncompetitive monoacylglycerol lipase (MAGL) inhibitor with IC50 of 28 uM against rat brain MAGL; elevates 2-AG levels and enhances 2-AG-mediated signaling in neurons, prolongs endocannabinoid-mediated changes in synaptic strength in acutely dissected rat hippocampal slices; showed anti-inflammatory and anti-nociceptive effect in murine model of acute inflammation. |
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