Oligomycin A

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP14686CAS No. ：579-13-5Purity：98%

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Chemical Properties&Biological Activity

CAS No.	579-13-5	Cat. No.	BCP14686
Name	Oligomycin A
Synonyms	MCH 32; MCH 32; MCH 32;
SMILES
Chemical Name
Formula	C45H74O11	M. Wt	791.06
Purity	98%	Storage	Store at 4-8°C
Description	Oligomycin A, also known as MCH 32, is an inhibitor of ATP synthase. Oligomycin A inhibits ATP synthase by blocking its proton channel (Fo subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production). The inhibition of ATP synthesis by oligomycin A will significantly reduce electron flow through the electron transport chain; however, electron flow is not stopped completely due to a process known as proton leak or mitochondrial uncoupling. This process is due to facilitated diffusion of protons into the mitochondrial matrix through an uncoupling protein such as thermogenin, or UCP1.

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