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ZCL 278 Chemical Structure

ZCL 278

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08398CAS No. :587841-73-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 587841-73-4 Cat. No. BCP08398
Name ZCL 278
Synonyms ZCL278;ZCL-278;
SMILES
Chemical Name
Formula C21H19BrClN5O4S2 M. Wt 584.89
Purity 98% Storage Store at 4-8°C
Description ZCL278 inhibits Cdc42 GTPase activity by the competition with GTP and inhibits Rac/Cdc42 phosphorylation in a time-dependent manner. ZCL278 (50 μM) inhibits Cdc42-mediated microspike formation and disrupts GM130-docked Golgi structures in serum-starved Swiss 3T3 fibroblasts. In addition, ZCL278 also suppresses Cdc42-mediated neuronal branching and growth cone dynamics as well as actin-based motility and migration in a metastatic prostate cancer PC-3 cell line without cytotoxicity.
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