Camostat mesilate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 59721-29-8 | Cat. No. | BCP06708 |
| Name | Camostat mesilate | ||
| Synonyms | FOY305;FOY 305;FOY-305;FOY-S980; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C21H26N4O8S | M. Wt | 494.52 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Camostat mesilate (500 mM) inhibits generation of TGF-beta by suppressing plasmin activity and reduces the activity of TGF-beta, which blocks in vitro activation of HSCs . Camostat mesilate (20 mM) combined with insulin results a significant hypoglycemic effect following large intestinal administration. Camostat mesilate (20 mM) is effective in reducing insulin degradation in both small and large intestinal homogenates of rats . Camostat mesilate (2 mM) inhibits MCP-1 and TNF- production in activated rat monocytes. Camostat mesilate (2 mM) inhibits proliferation and MCP-1 production of cultured rat PSCs. Camostat mesilate (1 mg/g) prevents pancreatic atrophy and improves pancreatic exocrine function of rat chronic pancreatitis induced by DBTC. Camostat mesilate (1 mg/g) inhibits chronic inflammation and pancreatic fibrosis induced by DBTC. Camostat mesilate (1 mg/g) inhibits the development of pancreatic fibrosis and PSCs activation in the pancreas induced by DBTC. Camostat mesilate (1 | ||
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