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Clorsulon Chemical Structure

Clorsulon

Data Sheet For research use only. Not for human use.
Cat. No. :BCP12136CAS No. :60200-06-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 60200-06-8 Cat. No. BCP12136
Name Clorsulon
Synonyms Curatrem;L631529;L 631529;L-631529;MK401;MK-401;MK 401; BRN 2821757; BRN2821757; BRN-2821757;
SMILES
Chemical Name
Formula C8H8Cl3N3O4S2 M. Wt 380.66
Purity 98% Storage Store at 4-8°C
Description Clorsulon is a competitive inhibitor of both 3-phosphoglycorate and ATP and had a Ki of 0.29 mM, inhibits glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro. [1] Clorsulon (a single dose of 15 mg/kg) is effective in removing over 90% of immature Fasciola hepatica from sheep (6 weeks after infection) and calves (8 weeks after infection). A 2.5 mg/kg dose removed over 90% of mature (16 weeks old) liver fluke from sheep. Clorsulon causes severe disruption to the tegument and gut of Fasciola hepatica after in vivo incubation.
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