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SB742457 Chemical Structure

SB742457

Data Sheet For research use only. Not for human use.
Cat. No. :BCP27653CAS No. :607742-69-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 607742-69-8 Cat. No. BCP27653
Name SB742457
Synonyms Intepirdine;GSK-742457;SB-742457;SB 742457;GSK742457;GSK 742457; RVT-101; RVT 101; RVT101;
SMILES
Chemical Name
Formula C19H19N3O2S M. Wt 353.44
Purity 98% Storage Store at 4-8°C
Description SB742457 , also known as Intepirdine, is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials. SB742457 can reverse age-related declines in delayed non-match-to-sample performance (DNMS). SB742457 shows increasing pro-cognitive effects in patients with AD.
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