SM16 New
Data Sheet
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| CAS No. | 614749-78-9 | Cat. No. | BCP30149 |
| Name | SM16 | ||
| Synonyms | SM-16; SM 16; | ||
| SMILES | O=C(C1(CC2)CCC2(C3=NC(C4=CC=C(OCO5)C5=C4)=C(C6=NC(C)=CC=C6)N3)CC1)N | ||
| Chemical Name | |||
| Formula | C25H26N4O3 | M. Wt | 430.51 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SM16 was shown to bind with high affinity to ALK5 kinase ATP binding site using a competitive binding assay and biacore analysis. SM16 blocked TGF-beta and activin-induced Smad2/3 phosphorylation and TGF-beta-induced plasminogen activator inhibitor (PAI)-luciferase activity in cells. | ||
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