CID-2011756
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CAS No. | 638156-11-3 | Cat. No. | BCP06823 |
Name | CID-2011756 | ||
Synonyms | CID2011756; CID 2011756; | ||
SMILES | |||
Chemical Name | |||
Formula | C22H21N2O3Cl | M. Wt | 396.87 |
Purity | 98% | Storage | Store at 4-8°C |
Description | CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells. CID 2011756, has pan-PKD inhibitory effects (PKD2 IC50 = 0.6±0.1; PKD3 IC50 = 0.7±0.2 ?M) with similar, albeit not identical, potencies which may be expected for an ATP competitive inhibitor. CID 2011756 was the most potent of the inhibitors with a cellular EC50 of 10±0.7 ?M (n = 3), an EC50 value comparable to that of our pre |
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