Cefuroxime Axetil New
Data Sheet
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| CAS No. | 64544-07-6 | Cat. No. | BCP10740 |
| Name | Cefuroxime Axetil | ||
| Synonyms | CCI 15641;CCI-15641;CCI15641;Ceftin; Zinnat; Elobact; Zinat; Cefuroxime 1-acetoxyethyl ester; | ||
| SMILES | CC(OC(=O)C)OC(=O)C1=C(CSC2N1C(=O)C2NC(=O)C(=NOC)C3=CC=CO3)COC(=O)N | ||
| Chemical Name | |||
| Formula | C20H22N4O10S | M. Wt | 510.47 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Cefuroxime Axetil is a second generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefuroxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefuroxime inhibits bacterial septum and cell wall synthesis formation. | ||
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