Brivanib New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 649735-46-6 | Cat. No. | BCP01777 |
| Name | Brivanib | ||
| Synonyms | BMS-540215;BMS540215;BMS 540215; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C19H19FN4O3 | M. Wt | 370.39 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Brivanib also inhibits VEGFR1 and FGFR-1 with IC50 of 0.38 μM and 0.148 μM. Brivanib is not sensitive to PDGFRβ, EGFR, LCK, PKCα or JAK-3 with IC50 all above 1900 nM. Brivanib could inhibit the proliferation of VEGF-stimulated HUVECs with IC50 of 40 nM, compared to 276 nM in FGF-stimulated HUVECs. On the other hand, Brivanib exhibits low activity to tumor cell lines. | ||
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