BIO
Data Sheet
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| CAS No. | 667463-62-9 | Cat. No. | BCP07234 |
| Name | BIO | ||
| Synonyms | GSK-3 Inhibitor IX;GSK 3 IX ; 6BIO; MLS 2052; MLS-2052; MLS2052; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C16H10BrN3O2 | M. Wt | 356.17 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Potent and selective, ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC50 values are 5, 83, 300, 320 and > 10 000 nM at GSK-3, CDK5/p25, CDK2/cyclin A, CDK1/cyclin B and other common kinases respectively). Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro; also promotes proliferation and dedifferentiation in cardiomyocytes. | ||
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