LDN-57444
Data Sheet
For research use only. Not for human use.
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| CAS No. | 668467-91-2 | Cat. No. | BCP07570 |
| Name | LDN-57444 | ||
| Synonyms | LDN 57444; LDN57444; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C17H11Cl3N2O3 | M. Wt | 397.64 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) activity (Ki = 0.4 μM). Causes cell death through the apoptosis pathway; increases levels of highly ubiquitinated proteins and decreases ubiquitin proteasome activity. Activity leads to dramatic alterations in synaptic protein distribution and spine morphology in vivo. | ||
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