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Eflornithine hydrochloride Chemical Structure

Eflornithine hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP11748CAS No. :68278-23-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 68278-23-9 Cat. No. BCP11748
Name Eflornithine hydrochloride
Synonyms Eflornithine HCl; DL-α-Difluoromethylornithine hydrochloride;DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride;
SMILES
Chemical Name
Formula C6H13ClF2N2O2 M. Wt 218.63
Purity 98% Storage Store at 4-8°C
Description Eflornithine Hydrochloride is the hydrochloride form of eflornithine, a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells.
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