IWP 2
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 686770-61-6 | Cat. No. | BCP09534 |
| Name | IWP 2 | ||
| Synonyms | IWP-2;IWP2; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C22H18N4O2S3 | M. Wt | 466.6 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: Inhibition of WNT signalling using FH535 and IWP-2 brought about a significant or borderline significant decrease in Caco-2(WISP2 KO) cell invasion (FH535 p=0.065) and (IWP-2 p=0.002) and negated the pro-invasive effect of targeting WISP2 in Caco-2 cells . IWP-2 decreased MKN28 cell proliferation, migration and invasion, and elevated caspase 3/7 activity. Further analysis demonstrated that IWP-2 downregulated the transcriptional activity of the Wnt/β-catenin signaling pathway and downregulated the expression levels of downstream Wnt/β-catenin target genes in MKN28 cells. Suppression of Wnt secretion from MSCs (IWP-2; 5 μmol/l) reduced the efficacy of ConT to induce phospho-LRP6 and to increase θ. | ||
Recommend Products
More >
-
-
-
-
-
Dalosirvat
Cat. No.：BCP44837
No.：1360540-81-3
Product Details -
-
Heparitin, sulfate
Cat. No.：BCP43695
No.：9050-30-0
Product Details -
Adavivint HCl
Cat. No.：BCP42884
No.：AdavivintHCl
Product Details -
-
-
Pyrvinium pamoate
Cat. No.：BCP38435
No.：3546-41-6
Product Details -
-
Adavivint
Cat. No.：BCP36799
No.：1467013-03-3
Product Details -
-
-
-
-
CHIR-99021 trihydrochloride
Cat. No.：BCP26069
No.：1782235-14-6
Product Details -
LP-922056
Cat. No.：BCP28623
No.：1365060-22-5
Product Details -
Tags:IWP 2 supplier,IWP 2 purchase,IWP 2 manufacturer,IWP 2 distributor,IWP 2 cost,IWP 2 buy,IWP 2 for sale