PDM2
Data Sheet
For research use only. Not for human use.
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| CAS No. | 688348-25-6 | Cat. No. | BCP29875 |
| Name | PDM2 | ||
| Synonyms | PDM-2;PDM 2; | ||
| SMILES | C1=CC(=CC=C1C=CC2=CC(=CC(=C2)Cl)Cl)Cl | ||
| Chemical Name | |||
| Formula | C14H9Cl3 | M. Wt | 283.58 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | PDM 2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM. PDM 2 is inactive as a ligand for the estrogen receptor even at 100 µM. As AhR knockout mice are insensitive to the carcinogenic effects of classical AhR ligands, PDM 2 is a potential therapeutic for the treatment for dioxin and other aryl hydrocarbon poisonings. | ||
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