Pimavanserin tartrate New
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CAS No. | 706782-28-7 | Cat. No. | BCP13711 |
Name | Pimavanserin tartrate | ||
Synonyms | Unii-na83F1sjsr;ACP-103 tartrate;ACP103 tartrate;ACP 103 tartrate; | ||
SMILES | CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.C(C(C(=O)O)O)(C(=O)O)O | ||
Chemical Name | |||
Formula | C54H74F2N6O10 | M. Wt | 1005.21 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist with pIC50 and pKi of 8.73 and 9.3, respectively.Pimavanserin, also known as ACP-103, is a non-dopaminergic atypical antipsychotic for the treatment of Parkinson's disease psychosis and schizophrenia. Pimavanserin has a unique mechanism of action relative to other antipsychotics, behaving as a selective inverse agonist of the serotonin 5-HT2A receptor, with 40-fold selectivity for this site over the 5-HT2C receptor and no significant affinity or activity at the 5-HT2B receptor or dopamine receptors. |
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