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Pimavanserin tartrate Chemical Structure

Pimavanserin tartrate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP13711CAS No. :706782-28-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 706782-28-7 Cat. No. BCP13711
Name Pimavanserin tartrate
Synonyms Unii-na83F1sjsr;ACP-103 tartrate;ACP103 tartrate;ACP 103 tartrate;
SMILES CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.C(C(C(=O)O)O)(C(=O)O)O
Chemical Name
Formula C54H74F2N6O10 M. Wt 1005.21
Purity 98% Storage Store at 4-8°C
Description Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist with pIC50 and pKi of 8.73 and 9.3, respectively.Pimavanserin, also known as ACP-103, is a non-dopaminergic atypical antipsychotic for the treatment of Parkinson's disease psychosis and schizophrenia. Pimavanserin has a unique mechanism of action relative to other antipsychotics, behaving as a selective inverse agonist of the serotonin 5-HT2A receptor, with 40-fold selectivity for this site over the 5-HT2C receptor and no significant affinity or activity at the 5-HT2B receptor or dopamine receptors.
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