Carbazeran
Data Sheet
For research use only. Not for human use.
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| CAS No. | 70724-25-3 | Cat. No. | BCP06512 |
| Name | Carbazeran | ||
| Synonyms | UK 31557;UK-31557;UK31557; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C18H24N4O4 | M. Wt | 360.412 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Carbazeran is an Aldehyde oxidase (AO) substrate and potent phosphodiesterase PDE-II and PDE-III inhibitor that produces concentration-dependent positive inotropic responses. Carbazeran shows chronotropic and inotropic effect in vivo (EC50 = 100 μM, ionotropic effects, independent of adrenergic mechanisms). It potently inhibits cAMP hydrolysis. In humans, the compound is almost completely cleared via 4-hydroxylation to the phthalazinone metabolite by AO. | ||
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