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CAS No. | 722456-31-7 | Cat. No. | BCP29113 |
Name | VAS2870 | ||
Synonyms | VAS 2870;VAS-2870; | ||
SMILES | |||
Chemical Name | |||
Formula | C18H12N6OS | M. Wt | 360.39 |
Purity | 98% | Storage | Store at 4-8°C |
Description | VAS2870 is a potent, specific NADPH oxidase (Nox) inhibitor; completely abolishes PDGF-mediated NAD(P)H oxidase activation and ROS production at 10-20 uM in vascular smooth muscle cells (VSMC); abrogates thalidomide stimulation of cardiomyogenesis; also impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells. |
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