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Pirarubicin Chemical Structure

Pirarubicin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP05223CAS No. :72496-41-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 72496-41-4 Cat. No. BCP05223
Name Pirarubicin
Synonyms THP-Adriamycin;Tepirubicin;Therarubiein; THP-Doxorubicin;
SMILES O=C1C2=C(C=CC=C2OC)C(C3=C(O)C4=C([C@@H](O[C@@]5([H])C[C@](N)[C@](O[C@@]6([H])OCCCC6)[C@](C)O5)C[C@@](C(CO)=O)(O)C4)C(O)=C31)=O
Chemical Name
Formula C32H37NO12 M. Wt 627.64
Purity 98% Storage Store at 4-8°C
Description Pirarubicin is an analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.
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