Rifabutin

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP20425CAS No. ：72559-06-9Purity：98%

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CAS No.	72559-06-9	Cat. No.	BCP20425
Name	Rifabutin
Synonyms	Ansamycin; LM-427; LM 427; LM427;
SMILES	CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C5=NC6(CCN(CC6)CC(C)C)N=C25)O)C
Chemical Name
Formula	C46H62N4O11	M. Wt	847
Purity	98%	Storage	Store at 4-8°C
Description	IC50 Value: Target: Antibacterial Rifabutin is primarily bactericidal antibiotic drug used to treat tuberculosis. Its effect on bacteria is based on the DNA-dependent RNA polymerase blocking drug rifamycin S., a semi-synthetic derivative. It is effective, for example, in highly resistant mycobacteria, Gram-positive bacteria (and some are effective against Gram-negative bacteria), but also against Mycobacterium tuberculosis, M. leprae, and M. avium intracellulare. Rifabutin is an antibiotic; antitumor. Rifabutin interferes with HSP-90 molecular chaperone, enhances ubiquitination and protein degradation, and inactivates bacterial RNA polymerase.