Mocetinostat
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 726169-73-9 | Cat. No. | BCP01814 |
| Name | Mocetinostat | ||
| Synonyms | MGCD0103;MGCD 0103;MGCD-0103; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H20N6O | M. Wt | 396.44 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MGCD0103 inhibits only a subset of the nine human recombinant HDACs, including HDAC1, HDAC2, HDAC3, and HDAC11 at nanomolar or low micromolar concentrations, in a dose-dependent manner. MGCD0103 reveals most potent inhibitory activity against human HDAC1 and HDAC2 enzymes in vitro, and it does not inhibit class II HDACs. The exocyclic amino group in MGCD0103 is necessary for enzyme inhibitory activity because HDAC-inhibitory activity against HDAC1 and HDAC2 is completely abolished with the desamino analogue. The inhibitory activity of MGCD0103 reaches the maximum plateau at 6 μM, and the maximal inhibitable enzyme pool affected by MGCD0103 is 75% of the total enzyme activity in HCT116 cells whereas NVP-LAQ824 inhibits almost 100% of that in these cells. In A549 cells, MGCD0103 also exhibits dose-dependent inhibition of HDAC activity in whole cells. | ||
Recommend Products
More >
-
-
Snail/HDAC-IN-1
Cat. No.：BCP48514
No.：2415281-52-4
Product Details -
-
-
Quisinostat HCl
Cat. No.：BCP44306
No.：1083078-98-1
Product Details -
-
Pracinostat Dihydrochloride
Cat. No.：BCP43352
No.：929016-98-8
Product Details -
-
Resminostat hydrochloride
Cat. No.：BCP39644
No.：1187075-34-8
Product Details -
SKLB-23bb
Cat. No.：BCP37616
No.：1815580-06-3
Product Details -
-
-
Sodium Butyrate
Cat. No.：BCP31813
No.：156-54-7
Product Details -
-
Remetinostat
Cat. No.：BCP30561
No.：946150-57-8
Product Details -
-
-
-
-
Belinostat
Cat. No.：BCP24610
No.：866323-14-0
Product Details
Tags:Mocetinostat supplier,Mocetinostat purchase,Mocetinostat manufacturer,Mocetinostat distributor,Mocetinostat cost,Mocetinostat buy,Mocetinostat for sale