Carvedilol

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP23386CAS No. ：72956-09-3Purity：98%

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CAS No.	72956-09-3	Cat. No.	BCP23386
Name	Carvedilol
Synonyms	Coreg;Dilatrend;BM 14190;BM-14190;BM14190;
SMILES
Chemical Name
Formula	C24H26N2O4	M. Wt	406.47
Purity	98%	Storage	Store at 4-8°C
Description	Carvedilol is a non-selective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers) indicated in the treatment of mild to moderate congestive heart failure (CHF). Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased.It blocks beta-1 and beta-2 adrenergic receptors as well as the alpha-1 adrenergic receptors. Carvedilol is a synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity. Carvedilol also reduces renin release through beta-blockade.