Omeprazole

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP13592CAS No. ：73590-58-6Purity：98%

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CAS No.	73590-58-6	Cat. No.	BCP13592
Name	Omeprazole
Synonyms	Antra;Losec;Prilosec;
SMILES
Chemical Name
Formula	C17H19N3O3S	M. Wt	345.42
Purity	98%	Storage	Store at 4-8°C
Description	Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger-Ellison syndrome. Omeprazole virtually eliminated intragastric acidity in all patients: the median 24 hour intragastric pH rose from 1.4 to 5.3 and the mean hourly hydrogen ion activity fell from 38.50 to 1.95 mmol(mEq)/1 (p less than 0.001). This inhibition of 24 hour intragastric acidity is more profound than that previously reported with either cimetidine 1 g daily or ranitidine 300 mg daily. The pharmacokinetics of omeprazole were studied in a group of healthy male subjects after single and repeated oral doses of 30 and 60 mg. Absorption of omeprazole from its enteric-coated formulation was unpredictable. There was a highly significant increase in the area under the plasma concentration time curve (AUC) after repeated dosing. Omeprazole increases its own relative availability following repeated dosing. This may be d