Pyronaridine

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP19128CAS No. ：74847-35-1Purity：98%

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Chemical Properties&Biological Activity

CAS No.	74847-35-1	Cat. No.	BCP19128
Name	Pyronaridine
Synonyms	Malaridine;Benzonaphthyridine 7351;
SMILES	OC1=C(CN2CCCC2)C=C(NC3=C4N=C(OC)C=CC4=NC5=CC(Cl)=CC=C53)C=C1CN6CCCC6
Chemical Name
Formula	C29H32ClN5O2	M. Wt	518.05
Purity	98%	Storage	Store at 4-8°C
Description	Pyronaridine, also known as Malaridine, is an antimalarial drug. It was first synthesized in 1970 and has been in clinical use in China since the 1980s. It is one of the components of the artemisinin combination therapy pyronaridine artesunate (Pyramax). Pyronaridine is a promising agent against erythrocytic stage of malaria parasites. It exhibited low toxicity and had no cross-resistance to chloroquine. Clinical administration in malaria cases showed high efficacy and mild side-effects.

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