Aztreonam
Data Sheet
For research use only. Not for human use.
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| CAS No. | 78110-38-0 | Cat. No. | BCP01737 |
| Name | Aztreonam | ||
| Synonyms | Azactam;Cayston; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C13H17N5O8S2 | M. Wt | 435.43 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Aztreonam(Azactam, Cayston) is a synthetic monocyclic beta-lactam antibiotic (a monobactam), with the nucleus based on a simpler monobactam isolated from Chromobacterium violaceum. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking. It has a very high affinity for penicillin-binding protein 3 (PBP-3) and mild affinity for PBP-1a. Aztreonam binds to the penicillin-binding proteins of gram-positive and anaerobic bacteria very poorly and is largely ineffective against them. | ||
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