Rosiptor New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP26168CAS No. ：782487-28-9Purity：98%

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CAS No.	782487-28-9	Cat. No.	BCP26168
Related Products	782487-29-0（Rosiptor acetate）
Name	Rosiptor
Synonyms	AQX-1125; AQX 1125; AQX1125;
SMILES	CC1(CCC(CC1CO)O)C2CCC3(C(C2CN)CCC3=C)C
Chemical Name
Formula	C20H35NO2	M. Wt	321.51
Purity	98%	Storage	Store at 4-8°C
Description	Rosiptor, also known as AQX-1125, is an activator of SHIP1, which controls the PI3K cellular signaling pathway. If the PI3K pathway is overactive, immune cells can produce an abundance of pro-inflammatory signaling molecules and migrate to and concentrate in tissues, resulting in excessive or chronic inflammation. SHIP1 is predominantly expressed in cells derived from bone marrow tissues, which are mainly immune cells. Therefore drugs that activate SHIP1 can reduce the function and migration of immune cells and have an anti-inflammatory effect. By controlling the PI3K pathway, Rosiptor reduces immune cell function and migration by targeting a mechanism that has evolved in nature to maintain homeostasis of the immune system.