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Masitinib Chemical Structure

Masitinib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP01820CAS No. ：790299-79-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 790299-79-5 Cat. No. BCP01820
Name Masitinib
Synonyms AB1010;Masivet;AB-1010;AB 1010;
SMILES O=C(NC1=CC=C(C)C(NC2=NC(C3=CC=CN=C3)=CS2)=C1)C4=CC=C(CN5CCN(C)CC5)C=C4
Chemical Name
Formula C28H30N6OS M. Wt 498.65
Purity 98% Storage Store at 4-8°C
Description Masitinib, also known as AB1010, is an orally bioavailable and multi-targeted protein tyrosine kinase inhibitor with potential antineoplastic activity. Masitinib selectively binds to and inhibits both the wild-type and mutated forms of the stem cell factor receptor (c-Kit; SCFR); platelet-derived growth factor receptor (PDGFR); fibroblast growth factor receptor 3 (FGFR3); and, to a lesser extent, focal adhesion kinase (FAK). As a consequence, tumor cell proliferation may be inhibited in cancer cell types that overexpress these receptor tyrosine kinases (RTKs).
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