Azelastine HCl
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CAS No. | 79307-93-0 | Cat. No. | BCP23404 |
Name | Azelastine HCl | ||
Synonyms | Allergodil;Azelastine hydrochloride; | ||
SMILES | |||
Chemical Name | |||
Formula | C22H24ClN3O.HCl | M. Wt | 418.36 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Azelastine HCl is a potent and selective H1-receptor antagonist, with antiallergic effects related to histamine antagonism, and further antiallergic and anti-inflammatory effects unrelated to H1-receptor binding. Azelastine HCl is an activator of NF-kB activator. Azelastine hydrochloride has been used in a study to investigate the potential of polymeric microspheres for treatment of allergic conjunctivitis. Azelastine is shown to block secretion of IL-6, IL-8, and TNF alpha from mast cells by inhibiting NF-κB activation. |
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