GSK256066
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 801312-28-7 | Cat. No. | BCP02627 |
| Name | GSK256066 | ||
| Synonyms | GSK-256066;GSK 256066; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C27H26N4O5S | M. Wt | 518.58 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GSK256066 is a slow and tight binding inhibitor of PDE4B with apparent IC50 of 3.2 pM. GSK256066 is an extremely potent inhibitor of LPS-stimulated TNFα production in PBMCs with pIC50 of 11.0 and IC50 of 10 pM and human whole-blood cultures with pIC50 of 9.90 and IC50 of 126 pM. GSK256066 is highly selective for PDE4 (>3.8 × 105-fold versus PDE1, PDE2, PDE3, PDE5, and PDE6 and >2.5 × 103-fold against PDE7). GSK256066 inhibits PDE4 isoforms A-D with equal affinity. | ||
Recommend Products
More >
-
-
Enpp-1-IN-14
Cat. No.：BCP47912
No.：2687222-59-7
Product Details -
-
Mirodenafil dihydrochloride
Cat. No.：BCP46802
No.：862189-96-6
Product Details -
BAY 2666605
Cat. No.：BCP45964
No.：2275774-60-0
Product Details -
Tetomilast
Cat. No.：BCP45927
No.：145739-56-6
Product Details -
Orismilast
Cat. No.：BCP45468
No.：1353546-86-7
Product Details -
Tovinontrine
Cat. No.：BCP44778
No.：2062661-53-2
Product Details -
Lenrispodun phosphate
Cat. No.：BCP44187
No.：1642303-38-5
Product Details -
-
-
-
ATX inhibitor 1
Cat. No.：BCP37626
No.：2225892-70-4
Product Details -
-
-
Mardepodect hydrochloride
Cat. No.：BCP35070
No.：2070014-78-5
Product Details -
DSR-141562
Cat. No.：BCP34050
No.：2007975-22-4
Product Details -
-
BIO-32546
Cat. No.：BCP28835
No.：1548743-66-3
Product Details -
Tags:GSK256066 supplier,GSK256066 purchase,GSK256066 manufacturer,GSK256066 distributor,GSK256066 cost,GSK256066 buy,GSK256066 for sale