Rifaximine
Data Sheet
For research use only. Not for human use.
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| CAS No. | 80621-81-4 | Cat. No. | BCP23005 |
| Name | Rifaximine | ||
| Synonyms | BRN 3584528; L105; L-105; Fatroximin; L 105SV; Normix; Rifacol; Rifamycin L 105; Rifaxidin; Rifaximin; Rifaxin; Ritacol; Rifaximin; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C43H51N3O11 | M. Wt | 785.89 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Rifaximin is a semisynthetic antibiotic based on rifamycin. It has poor oral bioavailability, meaning that very little of the drug will be absorbed into the blood stream when it is taken orally. Rifaximin is used in the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy, for which it received orphan drug status from the U.S. Food and Drug Administration in 1998. Rifaximin interferes with transcription by binding to the β-subunit of bacterial RNA polymerase. This results in the blockage of the translocation step that normally follows the formation of the first phosphodiester bond, which occurs in the transcription process. | ||
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