Nelotanserin

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP24992CAS No. ：839713-36-9Purity：98%

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Chemical Properties&Biological Activity

CAS No.	839713-36-9	Cat. No.	BCP24992
Name	Nelotanserin
Synonyms	APD125; APD-125; APD 125;
SMILES
Chemical Name
Formula	C18H15BrF2N4O2	M. Wt	437.24
Purity	98%	Storage	Store at 4-8°C
Description	Nelotanserin, also known as APD125, is a potent and selective human 5-hydroxytryptamine2A inverse agonist for the treatment of insomnia. Nelotanserin has low nanomolar potency on the 5-HT(2A) receptor with at least 30- and 5000-fold selectivity compared with 5-HT(2C) and 5-HT(2B) receptors, respectively. Nelotanserin produced statistically significant improvements in objective parameters of sleep maintenance and sleep consolidation and was well tolerated in adults with primary chronic insomnia.

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