A-769662 New Hot
Data Sheet
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| CAS No. | 844499-71-4 | Cat. No. | BCP01873 |
| Name | A-769662 | ||
| Synonyms | A 769662;A769662; | ||
| SMILES | N#CC1=C(O)C(C(C2=CC=C(C3=CC=CC=C3O)C=C2)=CS4)=C4NC1=O | ||
| Chemical Name | |||
| Formula | C20H12N2O3S | M. Wt | 360.39 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | A 769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 μM) that displays selectivity towards β1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 μM) and decreases plasma glucose and triglyceride levels in vivo. Also inhibits proliferation of mesenchymal stem cells, and impedes reprogramming of mouse embryonic fibroblasts to iPSCs. Activates autophagy. | ||
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