Pemafibrate
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CAS No. | 848259-27-8 | Cat. No. | BCP20864 |
Name | Pemafibrate | ||
Synonyms | K-877; K877; K 877; (R)-K 13675; (R)-K13675; (R)K-13675; | ||
SMILES | CC[C@@H](OC1=CC=CC(CN(C2=NC3=CC=CC=C3O2)CCCOC4=CC=C(OC)C=C4)=C1)C(O)=O | ||
Chemical Name | |||
Formula | C28H30N2O6 | M. Wt | 490.55 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Pemafibrate, also known as K-877 and (R)-K 13675, is a PPAR alpha agonist. (R)-K-13675 decreases the secretion of inflammatory markers without affecting cell proliferation or tube formation. Peroxisome proliferator-activated receptor-alpha (PPAR-alpha) is a key regulator of lipid and glucose metabolism and has been implicated in inflammation. (R)-K-13675 was associated with the inhibition of inflammatory responses without affecting cell proliferation or angiogenesis, and subsequently may induce an anti-atherosclerotic effect. |
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