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Pemafibrate Chemical Structure

Pemafibrate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP20864CAS No. :848259-27-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 848259-27-8 Cat. No. BCP20864
Name Pemafibrate
Synonyms K-877; K877; K 877; (R)-K 13675; (R)-K13675; (R)K-13675;
SMILES CC[C@@H](OC1=CC=CC(CN(C2=NC3=CC=CC=C3O2)CCCOC4=CC=C(OC)C=C4)=C1)C(O)=O
Chemical Name
Formula C28H30N2O6 M. Wt 490.55
Purity 98% Storage Store at 4-8°C
Description Pemafibrate, also known as K-877 and (R)-K 13675, is a PPAR alpha agonist. (R)-K-13675 decreases the secretion of inflammatory markers without affecting cell proliferation or tube formation. Peroxisome proliferator-activated receptor-alpha (PPAR-alpha) is a key regulator of lipid and glucose metabolism and has been implicated in inflammation. (R)-K-13675 was associated with the inhibition of inflammatory responses without affecting cell proliferation or angiogenesis, and subsequently may induce an anti-atherosclerotic effect.
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