BIIB021 New
Data Sheet
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| CAS No. | 848695-25-0 | Cat. No. | BCP02111 |
| Name | BIIB021 | ||
| Synonyms | CNF2024 ;BIIB 021;BIIB-021;CNF 2024;CNF-2024; | ||
| SMILES | NC1=NC(Cl)=C2N=CN(CC3=NC=C(C)C(OC)=C3C)C2=N1 | ||
| Chemical Name | |||
| Formula | C14H15ClN6O | M. Wt | 318.76 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BIIB021, also known as CNF2024, is an orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90 inhibitor CNF2024 specifically blocks active HSP90, inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival; this may result in the inhibition of cellular proliferation in susceptible tumor cell populations. | ||
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