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Trofinetide Chemical Structure

Trofinetide

Data Sheet For research use only. Not for human use.
Cat. No. :BCP17581CAS No. :853400-76-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 853400-76-7 Cat. No. BCP17581
Name Trofinetide
Synonyms NNZ-2566; NNZ 2566; NNZ2566;
SMILES CC1(CCCN1C(=O)CN)C(=O)NC(CCC(=O)O)C(=O)O
Chemical Name
Formula C13H21N3O6 M. Wt 315.32
Purity 98% Storage Store at 4-8°C
Description Trofinetide, also known as NNZ-2566, is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant. NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury. NNZ-2566 demonstrates neuroprotective efficacy in models of traumatic brain injury. NNZ-2566 significantly decreases injury-induced upregulation of inflammatory cytokines including TNF-α, IFN-γ, and IL-6. NNZ-2566 is a potential therapeutic agent for fragile X syndrome.
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