Trofinetide New
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CAS No. | 853400-76-7 | Cat. No. | BCP17581 |
Name | Trofinetide | ||
Synonyms | NNZ-2566; NNZ 2566; NNZ2566; | ||
SMILES | CC1(CCCN1C(=O)CN)C(=O)NC(CCC(=O)O)C(=O)O | ||
Chemical Name | |||
Formula | C13H21N3O6 | M. Wt | 315.32 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Trofinetide, also known as NNZ-2566, is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant. NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury. NNZ-2566 demonstrates neuroprotective efficacy in models of traumatic brain injury. NNZ-2566 significantly decreases injury-induced upregulation of inflammatory cytokines including TNF-α, IFN-γ, and IL-6. NNZ-2566 is a potential therapeutic agent for fragile X syndrome. |
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