Torezolid Phosphate Disodium New
Data Sheet
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| CAS No. | 856867-39-5 | Cat. No. | BCP15351 |
| Name | Torezolid Phosphate Disodium | ||
| Synonyms | Tedizolid phosphate disodium salt;DA 7218; TR 701;DA7218; TR701;DA-7218; TR-701; | ||
| SMILES | CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4CC(OC4=O)COP(=O)([O-])[O-])F.[Na+].[Na+] | ||
| Chemical Name | |||
| Formula | C17H16FN6Na2O7P | M. Wt | 494.29 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Tedizolid phosphate is a novel antibacterial prodrug with potent activity against Gram-positive pathogens. In vitro and in vivo studies demonstrated that the prodrug is rapidly converted by nonspecific phosphatases to the biologically active moiety tedizolid. Tedizolid phosphate is a next-generation oxazolidinone with activity against both methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus spp. Tedizolid has consistently shown potency advantages over linezolid against Gram-positive microorganisms including those with reduced susceptibility to linezolid. Of particular significance, minimum inhibitory concentrations of tedizolid appear to be largely unaffected by the chloramphenicol-florfenicol resistance (cfr) gene, which has been implicated in a number of published linezolid-resistant organism outbreaks. | ||
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