N106 New
Data Sheet
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| CAS No. | 862974-25-2 | Cat. No. | BCP48201 |
| Name | N106 | ||
| Synonyms | N-106; N 106; | ||
| SMILES | COC1=CC=C(C=C1)C2=NN=C(O2)NC3=NC4=C(C=CC=C4S3)OC | ||
| Chemical Name | |||
| Formula | C17H14N4O3S | M. Wt | 354.38 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | N106 directly activates the SUMO-activating enzyme, E1 ligase, and triggers intrinsic SUMOylation of SERCA2a. Decreased activity and expression of the cardiac sarcoplasmic reticulum calcium ATPase (SERCA2a), a critical pump regulating calcium cycling in cardiomyocyte, are hallmarks of heart failure. | ||
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