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CFMTI Chemical Structure

CFMTI

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP18264CAS No. ：864864-17-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 864864-17-5 Cat. No. BCP18264
Name CFMTI
Synonyms
SMILES
Chemical Name
Formula C19H16FN5O M. Wt 349.36
Purity 98% Storage Store at 4-8°C
Description In vitro: The IC50 values of CFMTI against human mGluR5 were 5400 ± 1200 nM, showing that the activity of CFMTI is more than 2000-fold weaker against human mGluR5 than against human mGluR1. CFMTI up to 10 μM exhibited no agonistic activity toward any group I mGluR subtypes (data not shown). The IC50 values of CFMTI were higher than 10 μM against all targets, such as NMDA receptors In vivo: CFMTI can dissolve in ethanol, polyethylene glycol 400, and distilled water (1:4:5, v/v/v) for intravenous administration. Oral administration of CFMTI inhibited DHPG-induced face-washing behavior in a dose-dependent manner. CFMTI produced dose-dependent inhibition of specific ex vivo binding of [3H]FTIDC to striatal and cerebellar slices in mice.
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