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CAS No. | 864953-29-7 | Cat. No. | BCP13226 |
Name | Fostemsavir | ||
Synonyms | BMS-663068;BMS663068; BMS 663068; | ||
SMILES | |||
Chemical Name | |||
Formula | C25H26N7O8P | M. Wt | 583.49 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BMS-663068 is a prodrug for BMS-626529 which binds to the viral envelope glycoprotein gp120 and interferes with attachment of the virus to the cellular CD4 receptor. Administration of BMS-663068 for 8 days with or without ritonavir resulted in substantial declines in plasma HIV-1 RNA levels and was generally well tolerated. Longer-term clinical trials of BMS-663068 as part of combination antiretroviral therapy are warranted. |
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