Almorexant
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CAS No. | 871224-64-5 | Cat. No. | BCP02616 |
Related Products | 913358-93-7(Almorexant HCl) | ||
Name | Almorexant | ||
Synonyms | ACT-078573;ACT 078573;ACT078573; | ||
SMILES | |||
Chemical Name | |||
Formula | C29H31F3N2O3 | M. Wt | 512.56 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Almorexant bound to a single saturable site on hOX(1) and hOX(2) with high affinity (K(d) of 1.3 and 0.17 nM, respectively. In Schild analyses using theinositol phosphates assay, almorexant acted as a competitive antagonist at hOX(1) and as a noncompetitive-like antagonist at hOX(2). In binding kinetic analyses, almorexant had fast association and dissociation rates at hOX(1), whereas it had a fast association rate and a remarkably slow dissociation rate at hOX(2) . |
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