Anacetrapib
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CAS No. | 875446-37-0 | Cat. No. | BCP02374 |
Name | Anacetrapib | ||
Synonyms | MK0859;MK 0859;MK-0859; | ||
SMILES | |||
Chemical Name | |||
Formula | C30H25F10NO3 | M. Wt | 637.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Anacetrapib is not only able to increase HDL-cholesterol, but also further decreases LDL-cholesterol when taken in combination with a statin. Anacetrapib dose-dependently and significantly decreases the transfer of CE from HDL3 to HDL2. Anacetrapib doesn't affect the amount of [14C]-dalcetrapibthiol bound to rhCETP. Anacetrapib decreases pre-β-HDL formation by more than 46%.Anacetrapib potently blocks CE and TG transfer in 95% human serum. |
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