ML221
Data Sheet
For research use only. Not for human use.
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| CAS No. | 877636-42-5 | Cat. No. | BCP28945 |
| Name | ML221 | ||
| Synonyms | ML 221; ML-221; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C17H11N3O6S | M. Wt | 385.35 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays. | ||
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